The Sativa dominant strain Sweet and Sour is a four-way cross between the strains Mexican Haze, Princess, Skunk #1, and Hawaiian Sativa. This strain is known to produce potent effects with lower THC percentages. According to reviewers, the high of Sweet and Sour starts with an uplifting and euphoric mood shift, which is accompanied by an increase of creative energy and focus. As the effects of Sweet and Sour start to settle in, users reported succumbing to a relaxing and hazy body stone that may induce couch lock. Others have enjoyed Sweet and Sour for its therapeutic effects as it may ease symptoms of depression, stress, glaucoma, Alzheimer's, inflammation, and nausea.